BCRF thanks the following for their unsolicited accolades, which have come not only from the scientific community but also from individuals who have chosen to support our mission and help us reach our goal: prevention and a cure for breast cancer in our lifetime.
"BCRF support made it possible for my lab to move into a new direction - to find breast cancer stem cells that are formed after breast cells become cancerous. This represented a research direction for which I had no dedicated support, making the BCRF grant invaluable. Destroying these cancer stem cells is the key to finding ways to achieve durable responses to anti-breast cancer therapy. Following up from these initial studies, researchers at the Broad Institute worked with my lab to begin the search for drugs that target the cancer stem cells. This work has now begun to produce highly interesting, novel agents for treating breast cancer and, quite possibly, other cancers as well."
Robert A. Weinberg, PhD
Founding Member, Whitehead Institute for Biomedical Research
"The pain and suffering caused by this disease can only be eliminated by the people working in the trenches identifying cell structure and finding targets to stem the tide of the disease. Many of these people are truly special. It was for this reason that I specified BCRF as the designated charity for those wanting to make donations in Debbie's name."
Robert Mazer, attorney, husband of the late Debra Moses
"The Breast Cancer Research Foundation is a "first-of-its-kind and still-leading organization [that] recognized that new knowledge in the laboratory is worthless to people if it is not translated into clinical research, clinical trials and clinical applications. The BCRF now supports investigators in the United States, Canada, Belgium, France, Spain, the United Kingdom, Israel and Latin America. Each year, it hosts a major event in New York, coupling a scientific symposium with a public educational panel, demonstrating the patient-oriented focus of the organization. The scientists chosen to participate in the BCRF are all established investigators of notable achievement, but they are asked to propose truly innovative research--breaking new ground, finding new directions, taking rational chances--so as to move the field forward with more speed, more excitement. This approach has not only yielded concrete progress but has inspired uncountable translational research initiatives throughout the world."
Larry Norton, MD
Deputy Physician-in-Chief, Director of Breast Cancer Programs, Memorial Sloan-Kettering Cancer Center
Chairman, BCRF Executive Board of Scientific Advisors
"The notification about The BCRF grant award was doubly appreciated because NIH grants are more difficult to obtain right now than I can ever recall. These times are especially difficult for young scientists at the beginning of their careers. Part of the BCRF funding to our lab helps to support a brilliant young scientist who has a very promising career."
Judah Folkman, MD
Director, Vascular Biology Program, Children's Hospital
Professor of Cell Biology, Harvard Medical School
"Have I told you recently how grateful we are to you? BCRF changed my life as a scientist by freeing me from the tyranny of intellectually
safe projects. BCRF saved the lives of many women by making out-of-the-box work possible by us all. It takes a village. Please give
our thanks to everyone in yours. We really mean it."
Mary-Claire King, PhD
The New York Breast Cancer Study
American Cancer Society Professor, Departments of Medicine and
University of Washington
"One of the great advantages offered by Breast Cancer Research Foundation funding is the immense flexibility it offers researchers to perform exciting, cutting edge research studies without the prolonged attempts at obtaining research funding from relatively unimaginative study sections." [In the course of describing a new program, Friends for Life, established with BCRF funding, he went on to say:] "It is important to emphasize that, had this case control study been performed in a standard fashion, the time required to obtain federal grant approval, and the cost of performing the study, would have implied a multi-year, perhaps multi-million dollar process. With the support of the BCRF grant, and with the grassroots Friends for Life organization, a huge sample and epidemiologic database has been created for future studies."
George W. Sledge, Jr.
Ballve Professor of Medicine and Pathology
Chair, Breast Committee
Eastern Cooperative Oncology Group
"I am truly appreciative of the BCRF's great work and the continued support of our research. We never take this support for granted, but work diligently to use these funds in novel ways that will ultimately lead to the conquest of breast cancer. The BCRF has meant so much to my personal research career as well as to UNC and its Cancer Center. It is a high compliment when a scientific board of such quality decides to fund one's work."
H. Shelton Earp III, MD
Professor & Director, Lineberger Comprehensive Cancer Center;
Professor of Medicine and Pharmacology, The School of Medicine, The University of North Carolina at Chapel Hill
"You are to be congratulated for providing some of the best minds in breast cancer research with the funds and freedom that will permit them to be 'creative'. Your efforts are bound to have a major impact on the progress toward the conquest of breast cancer."
Bernard Fisher, MD
Scientific Director of the National Surgical Adjuvant Breast and Bowel Project (NSABP)
BCRF 2003 Jill Rose Awardee
"You have collected the best brain trust in the country, perhaps the world. BCRF is an important force driving for solutions in breast cancer research."
Michael J. Zinner, MD
Surgeon-in-Chief, Brigham & Women's Hospital and Moseley Professor of Surgery, Harvard Medical School
"Catalyst exactly explains the role BCRF has had for our research. Because BCRF funding was quick and unencumbered, we were able to begin our work on the New York Breast Cancer Project immediately and make rapid progress."
Mary-Claire King, PhD
American Cancer Society
Professor of Medicine and Genetics,
University of Washington
"We wish to recognize and thank you for the inspired example of your leadership, compassion, and generosity, and for the outstanding role you have played and continue to play in the fight against breast cancer."
on presentation to Evelyn Lauder of the 2003 Brooke Astor Award for Outstanding Contribution to the Advancement of Science, at Rockefeller University in May 2003
"In my view, the factors that distinguish the grant activities of
The Breast Cancer Research Foundation include: 1) focus on
translational research, 2) willingness to fund high risk - high impact
ideas, 3) flexibility in how funds may be allocated, 4) short application
and short review process, and 5) application by invitation only."
Nancy E. Davidson, MD
Breast Cancer Research
Chair in Oncology,
Johns Hopkins University
"Your awards support leaders in translational science and assume that they will be able to best dispense the funds. This is invaluable. Most grants require a year's lead time before ideas can be funded. The BCRF funds allow you to plan ideas a few months ahead, and are flexible in support. The awards also come with the promise of continuity to explore new ideas as they arise. I also really appreciate the annual awards ceremony and the expression of thanks to the scientists. We don't often get that and it really is rewarding and inspiring to see that people appreciate us, even if we don't come up with all of the answers. It is an expression of thanks for the efforts we put forward to try to find answers."
J. Laura Esserman, MD
Director, Carole Franc Buck Breast Cancer Center,
University of California at San Francisco
"The impact [of BCRF funding] has been enormous. We have undertaken a project that is 'capital-intensive' and that would not have received federal funding because of its perceived risky nature. This project then progressed to the point where it was no longer viewed as risky, and the federal government funds a portion of it (although not near its true costs.) The clinical value of our goals, which we expect to complete within the year, should be enormous."
Michael Wigler, PhD
Principal Investigator, Cold Spring Harbor Laboratory
"The best part of BCRF grants is the focus on bringing basic research and clinical research together, and the understanding that ideas need time for proper development. The BCRF is unique in its understanding of the reality of nurturing and funding researchers with an outstanding track record of accomplishments, and with ongoing active research and clinical ideas that are necessary to reach the ultimate goal of curing this disease. One of the best parts of the BCRF is also the group itself, a group that distinguishes itself by professionalism, focus, and clear goals for success."
Edith Perez, MD
Chair, North Central Cancer Treatment Group Breast Committee, The Mayo Clinic, Jacksonville, Florida
"Grant support from the BCRF has been enormously helpful in several ways: first, it has provided 'seed' funds for novel ideas, so that feasibility studies could be initiated and preliminary data could be developed. In this manner, our group was able to develop more comprehensive grant proposals to federal agencies, or the Department of Defense. Second, we have been able to develop novel ideas that usually do not fare well in the traditional NIH granting system. Third, the relatively simple and expeditious application and award process provides rapid access to funds necessary to proceed with a good idea in a highly competitive system."
Gabriel N. Hortobagyi, MD
Professor and Chairman, Department of Breast Medical Oncology, The University of Texas--MD Anderson Cancer Center